Martin Scorsese traces the roots of the blues from the Mississippi Delta back to West Africa, journeying from the juke joints of Mississippi to the banks of the Niger River in Mali. Featuring performances by Corey Harris, Taj Mahal, Keb’ Mo’, and Ali Farka Touré, along with rare archival footage of blues legends like Son House and Muddy Waters, the film offers a lyrical portrait of the music’s deep African origins.